The Misdiagnosis of Hypertension: The Role of Patient Anxiety | Anxiety Disorders | JAMA Internal Medicine | JAMA Network

Abstract
Background The white coat effect (defined as the difference between blood pressure [BP] measurements taken at the physician’s office and those taken outside the office) is an important determinant of misdiagnosis of hypertension, but little is known about the mechanisms underlying this phenomenon. We tested the hypothesis that the white coat effect may be a conditioned response as opposed to a manifestation of general anxiety.

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